6 Facts You Need to Know About LFT (Liver Function Test)


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The vital medical diagnostic tool known as the Liver Function Test, or LFT, offers invaluable insights into the condition and operation of the liver. To ensure that the liver is functioning properly, which is a crucial organ involved in a variety of metabolic activities, careful monitoring is necessary. Let’s look at some crucial details regarding LFT, its importance, its parts, its interpretation, and its function in preserving general health are covered in this article. The LFT test price in Pakistan is about Rs 1000-3000.

1- Understanding LFT and Its Components

LFTs are crucial blood tests that evaluate the condition of the liver. Measuring liver enzymes like ALT and AST, which signify liver damage or inflammation, is one of them. Bilirubin measurements highlight bile production issues, whereas total protein and albumin measurements evaluate the liver’s capacity for protein synthesis. Bile duct problems can be discovered using ALP levels. Together, these elements provide information on liver health, assisting in the identification and treatment of liver illnesses. Regular monitoring guarantees prompt action and maintains liver function.

2- Guidelines for LFT

LFTs, or liver function tests, are important blood tests that reveal important details regarding the condition of the liver. There are some rules that should be adhered to in order to ensure appropriate interpretation and clinical relevance. The patient’s medical history, especially any liver disorders, drug use, and alcohol use, must be taken into account first because these can affect the results of the LFT. To preserve uniformity in measurements, LFTs are best performed in the morning following an overnight fast.

Several factors, including liver enzymes (ALT and AST), bilirubin levels, albumin, total protein, and alkaline phosphatase (ALP), are evaluated when interpreting LFT data. Unusual levels of these markers may be a sign of liver diseases such as cirrhosis, hepatitis, or obstructive jaundice. Healthcare practitioners should evaluate LFT results combined with clinical symptoms and other diagnostic tests to make an accurate diagnosis. This integrated approach emphasizes the value of individualized liver health evaluation while ensuring suitable treatment strategies.

3- Preparation and Procedure

Fasting for roughly 8 to 12 hours before a liver function test (LFT) is required to ensure reliable findings by removing the impact of recent dietary intake. Additionally, it’s important to let your doctor know if you take any vitamins or drugs because they may alter your LFT findings.

The LFT process involves using a needle to take blood from a vein in your arm. The blood is subsequently delivered to a lab for examination. The panel typically includes evaluations of bilirubin levels, albumin, total protein, alkaline phosphatase (ALP), and liver enzymes, including ALT and AST. These measurements give detailed information about the condition of the liver.

Fasting and medication declaration are simple steps in the LFT preparation process. Blood is drawn during the minimally invasive process, and the results are used to measure liver health and precisely diagnose any probable liver-related disorders.

4- How to Interpret LFT Results

Understanding the reference ranges and the individual’s health situation in depth is essential for properly interpreting LFT findings. Elevated ALT, AST, ALP, or bilirubin levels may be a sign of liver damage, infection, or other liver-related problems. However, anomalous outcomes might also be caused by causes unrelated to the liver, underscoring the value of a thorough analysis.

5- Limitations and Further Action

It’s crucial to understand that LFT results are not always unambiguous signs of liver disease. A diagnosis may need to be confirmed through additional testing, such as imaging examinations or blood tests, if the results are abnormal. False positives and false negatives are also conceivable, underscoring the importance of clinical competence in determining the best course of action for follow-up.

6- Observation and Lifestyle Choices

LFT is a useful method for tracking the condition of the liver over time. Regular testing can aid in early change detection and prompt response. People who are at risk for liver disease should think about changing their lifestyles to reduce their alcohol use, maintain a healthy weight, and take care of underlying medical disorders.

Regular LFT testing enables medical professionals to monitor long-term changes in liver function. Early indicators of liver damage or disease can be found before they worsen by identifying modest changes in liver enzyme levels or other markers. Then, prompt actions can be taken to stop future damage, such as dietary changes, medication adjustments, or focused treatments.


The Liver Function Test is a crucial instrument for evaluating the liver’s health and function, an important organ that is involved in many body functions. Making informed healthcare decisions requires a thorough understanding of the LFT’s components, indications, preparation, and outcomes. While abnormal LFT readings can be concerning, they also act as a warning sign for possible liver problems that can be treated with medical attention, a change in lifestyle, and continued monitoring. People can actively protect their liver health and general well-being by being knowledgeable about LFT and its significance.


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